Honey bee venom contains at least 18 active substances.
Melittin, the most prevalent substance, is one of the most potent anti-inflammatory agents known (100 times more potent than hydrocortisol).
Adolapin is another strong anti-inflammatory substance, and inhibits cyclooxygenase; it thus has analgesic activity as well. Apamin inhibits complement C3 activity, and blocks calcium-dependent potassium channels, thus enhancing nerve transmission.
Other substances, such as Compound X, Hyaluronidase, Phospholipase A2, Histamine, and Mast Cell Degranulating Protein (MSDP), are involved in the inflammatory response of venom, with the softening of tissue and the facilitation of flow of the other substances. Finally, there are measurable amounts of the neurotransmitters Dopamine, Norepinephrine and Seratonin.
BV Relief bee venom cream. works as a natural anti-inflammatory carried right into sore muscles and painful joints via deep-penetrating emu oil and cooling aloe vera.
The Bee venom in BV relief appears to act like cortisone: in fact bee venom is effective in all afflictions that are influenced by cortisone.
Bee venom is not accompanied by side effects normally associated with cortisone, apart from rare allergic reactions.
BV Relief bee venom cream contains patented New Zealand bee venom collected without harming the bees.